Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed millions of people and continues to cause massive global upheaval. Coronaviruses are positive-strand RNA viruses with an unusually large genome of ~30 kb. They express an RNA-dependent RNA polymerase and a cohort of other replic...

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Detalles Bibliográficos
Autores principales: Malone, Brandon, Urakova, Nadya, Snijder, Eric J., Campbell, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613731/
https://www.ncbi.nlm.nih.gov/pubmed/34824452
http://dx.doi.org/10.1038/s41580-021-00432-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613731/
https://www.ncbi.nlm.nih.gov/pubmed/34824452
http://dx.doi.org/10.1038/s41580-021-00432-z

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