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Selective Recognition of a Single HIV-1 G-Quadruplex by Ultrafast Small-Molecule Screening
[Image: see text] G-quadruplexes (G4s) are implicated in pathological processes such as cancer and infective diseases. Their targeting with G4-ligands has shown therapeutic capacity. Most of the current G4-ligands are planar molecules, do not discriminate among G4s, and have poor druglike properties...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613737/ https://www.ncbi.nlm.nih.gov/pubmed/34762806 http://dx.doi.org/10.1021/acs.analchem.0c04106 |