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WSF-CT-11, a Sesquiterpene Derivative, Activates AMP-Activated Protein Kinase with Anti-diabetic Effects in 3T3-L1 Adipocytes

[Image: see text] Background: AMP-activated protein kinase (AMPK) is a therapeutic target against type II diabetes (T2D). Synthetic sesquiterpene derivatives were investigated to identify novel AMPK activators as anti-diabetic drugs because the leading drugs like metformin and thiazolidinediones (TZ...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Wang, Yunyun, Zhang, Zhijie, Wang, Shifa, Li, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613856/
https://www.ncbi.nlm.nih.gov/pubmed/34841171
http://dx.doi.org/10.1021/acsomega.1c05061