Agonist/Antagonist Activity of Oxytocin Variants Obtained from Free Cyclic Peptide Libraries Generated via Amino Acid Substitution

[Image: see text] We established a method for synthesizing a free cyclic peptide library via peptide array synthesis to demonstrate the sequence activity of cyclic peptides. Variants of the cyclic nonapeptide oxytocin (OXT) were synthesized via residue substitution. Natural amino acids (AAs) were cl...

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Detalles Bibliográficos
Autores principales: Kinoshita, Remi, Kozaki, Ikko, Shimizu, Kazunori, Shibata, Takahiro, Ochiai, Akihito, Honda, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613857/
https://www.ncbi.nlm.nih.gov/pubmed/34841168
http://dx.doi.org/10.1021/acsomega.1c04982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613857/
https://www.ncbi.nlm.nih.gov/pubmed/34841168
http://dx.doi.org/10.1021/acsomega.1c04982

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