The effect of hypoxia on PD-L1 expression in bladder cancer

INTRODUCTION: Recent data has demonstrated that hypoxia drives an immunosuppressive tumour microenvironment (TME) via various mechanisms including hypoxia inducible factor (HIF)-dependent upregulation of programmed death ligand 1 (PD-L1). Both hypoxia and an immunosuppressive TME are targetable inde...

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Detalles Bibliográficos
Autores principales: Smith, Vicky, Mukherjee, Debayan, Lunj, Sapna, Choudhury, Ananya, Hoskin, Peter, West, Catharine, Illidge, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613983/
https://www.ncbi.nlm.nih.gov/pubmed/34819027
http://dx.doi.org/10.1186/s12885-021-09009-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613983/
https://www.ncbi.nlm.nih.gov/pubmed/34819027
http://dx.doi.org/10.1186/s12885-021-09009-7

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