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AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment

Non-alcoholic fatty liver disease (NAFLD) is a complication of childhood obesity and an oxidative stress-related multisystem disease. A mitochondria-targeting hydrogen sulfide (H(2)S) donor AP39 has antioxidant property, while the mechanism underlying the function of AP39 on pediatric NAFLD remains...

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Detalles Bibliográficos
Autores principales: Yu, Yue, Ye, Shu-Ming, Liu, De-Yun, Yang, Li-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614011/
https://www.ncbi.nlm.nih.gov/pubmed/34305077
http://dx.doi.org/10.1538/expanim.21-0056