Cargando…

An L314Q mutation in Map3k1 gene results in failure of eyelid fusion in the N-ethyl-N-nitrosourea-induced mutant line

In this study, we describe an N-ethyl-N-nitrosourea-induced mouse model with a corneal opacity phenotype that was associated with “eye open at birth” (EOB). Histological and immunohistochemistry staining analysis showed abnormal differentiation of the corneal epithelial cells in the mutant mice. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Bing, Wang, Hong-Ling, Chen, Rui, Chen, Li, Yang, Shun, Wang, Yi, Xue, Zheng-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614015/
https://www.ncbi.nlm.nih.gov/pubmed/34078823
http://dx.doi.org/10.1538/expanim.21-0005