Characterization of a novel glucocorticoid-resistant human B-cell acute lymphoblastic leukemia cell line, with AMPK, mTOR and fatty acid synthesis pathway inhibition

BACKGROUND: Acquired glucocorticoid (GC) resistance remains the main obstacle in acute lymphoblastic leukemia (ALL) therapy. The aim of the present study was to establish a novel GC-resistant B-ALL cell line and investigate its biological characteristics. METHODS: A cell culture technique was used t...

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Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Zuo, Chuan, Gu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614043/
https://www.ncbi.nlm.nih.gov/pubmed/34823530
http://dx.doi.org/10.1186/s12935-021-02335-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614043/
https://www.ncbi.nlm.nih.gov/pubmed/34823530
http://dx.doi.org/10.1186/s12935-021-02335-7

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