Chemically Tuning the Antigen Release Kinetics from Spherical Nucleic Acids Maximizes Immune Stimulation

[Image: see text] Cancer vaccine structure is emerging as an important design factor that offers tunable parameters to enhance the targeted immune response. We report the impact of altering the antigen release rate from spherical nucleic acid (SNA) vaccines—nanoparticles with a liposomal core and su...

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Detalles Bibliográficos
Autores principales: Skakuj, Kacper, Teplensky, Michelle H., Wang, Shuya, Dittmar, Jasper W., Mirkin, Chad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614098/
https://www.ncbi.nlm.nih.gov/pubmed/34841057
http://dx.doi.org/10.1021/acscentsci.1c00779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614098/
https://www.ncbi.nlm.nih.gov/pubmed/34841057
http://dx.doi.org/10.1021/acscentsci.1c00779

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