Probe Confined Dynamic Mapping for G Protein-Coupled Receptor Allosteric Site Prediction

[Image: see text] Targeting G protein-coupled receptors (GPCRs) through allosteric sites offers advantages over orthosteric sites in identifying drugs with increased selectivity and potentially reduced side effects. In this study, we developed a probe confined dynamic mapping protocol that allows th...

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Detalles Bibliográficos
Autores principales: Ciancetta, Antonella, Gill, Amandeep Kaur, Ding, Tianyi, Karlov, Dmitry S., Chalhoub, George, McCormick, Peter J., Tikhonova, Irina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614102/
https://www.ncbi.nlm.nih.gov/pubmed/34841058
http://dx.doi.org/10.1021/acscentsci.1c00802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614102/
https://www.ncbi.nlm.nih.gov/pubmed/34841058
http://dx.doi.org/10.1021/acscentsci.1c00802

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