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Aldosterone and the mineralocorticoid receptor in renal injury: A potential therapeutic target in feline chronic kidney disease

There is a growing body of experimental and clinical evidence supporting mineralocorticoid receptor (MR) activation as a powerful mediator of renal damage in laboratory animals and humans. Multiple pathophysiological mechanisms are proposed, with the strongest evidence supporting aldosterone‐induced...

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Detalles Bibliográficos
Autores principales: Spencer, Sarah, Wheeler‐Jones, Caroline, Elliott, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614124/
https://www.ncbi.nlm.nih.gov/pubmed/32128854
http://dx.doi.org/10.1111/jvp.12848