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Off-Target Expression of Cre-Dependent Adeno-Associated Viruses in Wild-Type C57BL/6J Mice

Adeno-associated viruses (AAVs) are a commonly used tool in neuroscience to efficiently label, trace, and/or manipulate neuronal populations. Highly specific targeting can be achieved through recombinase-dependent AAVs in combination with transgenic rodent lines that express Cre-recombinase in speci...

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Detalles Bibliográficos
Autores principales: Botterill, Justin J., Khlaifia, Abdessattar, Walters, Brandon J., Brimble, Mark A., Scharfman, Helen E., Arruda-Carvalho, Maithe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614227/
https://www.ncbi.nlm.nih.gov/pubmed/34785571
http://dx.doi.org/10.1523/ENEURO.0363-21.2021