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PK/PD Analysis by Nonlinear Mixed-Effects Modeling of a Marbofloxacin Dose Regimen for Treatment of Goat Mastitis Produced by Coagulase-Negative Staphylococci

SIMPLE SUMMARY: Coagulase-negative staphylococci are main pathogens that produce goat mastitis. Marbofloxacin is a third-generation fluoroquinolone approved to treat mastitis in animals. Since the efficacy of an antimicrobial is related with its concentration in the site of infection, and the latter...

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Detalles Bibliográficos
Autores principales: Lorenzutti, Augusto Matías, Vico, Juan Pablo, Serrano-Rodríguez, Juan Manuel, Himelfarb, Martín Alejandro, Andrés-Larrea, Manuel Ignacio San, de Lucas-Burneo, José Julio, Litterio, Nicolás Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614466/
https://www.ncbi.nlm.nih.gov/pubmed/34827830
http://dx.doi.org/10.3390/ani11113098