Cargando…

Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome

Hutchinson-Gilford progeria syndrome (HGPS) is a rare disorder characterized by premature aging and death mainly because of myocardial infarction, stroke, or heart failure. The disease is provoked by progerin, a variant of lamin A expressed in most differentiated cells. Patients look healthy at birt...

Descripción completa

Detalles Bibliográficos
Autores principales: Sánchez-López, Amanda, Espinós-Estévez, Carla, González-Gómez, Cristina, Gonzalo, Pilar, Andrés-Manzano, María J., Fanjul, Víctor, Riquelme-Borja, Raquel, Hamczyk, Magda R., Macías, Álvaro, del Campo, Lara, Camafeita, Emilio, Vázquez, Jesús, Barkaway, Anna, Rolas, Loïc, Nourshargh, Sussan, Dorado, Beatriz, Benedicto, Ignacio, Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614561/
https://www.ncbi.nlm.nih.gov/pubmed/34694158
http://dx.doi.org/10.1161/CIRCULATIONAHA.121.055313