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Effect on Osteogenic Differentiation of Genetically Modified IL4 or PDGF-BB Over-Expressing and IL4-PDGF-BB Co-Over-Expressing Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro

The use of genetically modified (GM) mesenchymal stromal cells (MSCs) and preconditioned MSCs (pMSCs) may provide further opportunities to improve the outcome of core decompression (CD) for the treatment of early-stage osteonecrosis of the femoral head (ONFH). GM interleukin-4 (IL4) over-expressing...

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Detalles Bibliográficos
Autores principales: Tsubosaka, Masanori, Maruyama, Masahiro, Huang, Elijah Ejun, Zhang, Ning, Utsunomiya, Takeshi, Gao, Qi, Shen, Huaishuang, Li, Xueping, Kushioka, Junichi, Hirata, Hirohito, Yao, Zhenyu, Yang, Yunzhi Peter, Goodman, Stuart B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614682/
https://www.ncbi.nlm.nih.gov/pubmed/34821731
http://dx.doi.org/10.3390/bioengineering8110165