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Effect on Osteogenic Differentiation of Genetically Modified IL4 or PDGF-BB Over-Expressing and IL4-PDGF-BB Co-Over-Expressing Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro
The use of genetically modified (GM) mesenchymal stromal cells (MSCs) and preconditioned MSCs (pMSCs) may provide further opportunities to improve the outcome of core decompression (CD) for the treatment of early-stage osteonecrosis of the femoral head (ONFH). GM interleukin-4 (IL4) over-expressing...
Autores principales: | Tsubosaka, Masanori, Maruyama, Masahiro, Huang, Elijah Ejun, Zhang, Ning, Utsunomiya, Takeshi, Gao, Qi, Shen, Huaishuang, Li, Xueping, Kushioka, Junichi, Hirata, Hirohito, Yao, Zhenyu, Yang, Yunzhi Peter, Goodman, Stuart B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614682/ https://www.ncbi.nlm.nih.gov/pubmed/34821731 http://dx.doi.org/10.3390/bioengineering8110165 |
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