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Reverse Ordered Sequential Mechanism for Lactoperoxidase with Inhibition by Hydrogen Peroxide
Lactoperoxidase (LPO, Fe(III) in its resting state in the absence of substrates)—an enzyme secreted from human mammary, salivary, and other mucosal glands—catalyzes the oxidation of thiocyanate (SCN(−)) by hydrogen peroxide (H(2)O(2)) to produce hypothiocyanite (OSCN(−)), which functions as an antim...
Autores principales: | Cupp-Sutton, Kellye, Ashby, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614691/ https://www.ncbi.nlm.nih.gov/pubmed/34829517 http://dx.doi.org/10.3390/antiox10111646 |
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