Bis(Tryptophan) Amphiphiles Form Ion Conducting Pores and Enhance Antimicrobial Activity against Resistant Bacteria

The compounds referred to as bis(tryptophan)s (BTs) have shown activity as antimicrobials. The hypothesis that the activity of these novel amphiphiles results from insertion in bilayer membranes and transport of cations is supported by planar bilayer voltage-clamp studies reported herein. In additio...

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Detalles Bibliográficos
Autores principales: Patel, Mohit, Negin, Saeedeh, Meisel, Joseph, Yin, Shanheng, Gokel, Michael, Gill, Hannah, Gokel, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614774/
https://www.ncbi.nlm.nih.gov/pubmed/34827329
http://dx.doi.org/10.3390/antibiotics10111391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614774/
https://www.ncbi.nlm.nih.gov/pubmed/34827329
http://dx.doi.org/10.3390/antibiotics10111391

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