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Terretonin as a New Protective Agent against Sepsis-Induced Acute Lung Injury: Impact on SIRT1/Nrf2/NF-κBp65/NLRP3 Signaling

SIMPLE SUMMARY: Acute lung injury (ALI) is a severe inflammatory pulmonary disorder that still causes a high mortality rate. As the current therapeutic strategies have not been effective in reducing ALI-associated mortality, searching for a novel pharmacological candidate that can suppress ALI is ma...

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Detalles Bibliográficos
Autores principales: Mohamed, Gamal A., Ibrahim, Sabrin R. M., El-Agamy, Dina S., Elsaed, Wael M., Sirwi, Alaa, Asfour, Hani Z., Koshak, Abdulrahman E., Elhady, Sameh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614783/
https://www.ncbi.nlm.nih.gov/pubmed/34827212
http://dx.doi.org/10.3390/biology10111219