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Computer-Aided Design for Identifying Anticancer Targets in Genome-Scale Metabolic Models of Colon Cancer

SIMPLE SUMMARY: Discovery of anticancer targets with minimal side effects is a major challenge in drug discovery and development. This study developed a fuzzy optimization framework for identifying anticancer targets. The framework was applied to identify not only gene regulator targets but also met...

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Detalles Bibliográficos
Autores principales: Cheng, Chao-Ting, Wang, Tsun-Yu, Chen, Pei-Rong, Wu, Wu-Hsiung, Lai, Jin-Mei, Chang, Peter Mu-Hsin, Hong, Yi-Ren, Huang, Chi-Ying F., Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614794/
https://www.ncbi.nlm.nih.gov/pubmed/34827109
http://dx.doi.org/10.3390/biology10111115