γ-Glutamyl-Transpeptidase-Resistant Glutathione Analog Attenuates Progression of Alzheimer’s Disease-like Pathology and Neurodegeneration in a Mouse Model

Oxidative stress in Alzheimer’s disease (AD) is mediated, in part, by the loss of glutathione (GSH). Previous studies show that γ-glutamyl transpeptidase (GGT)-resistant GSH analog, Ψ-GSH, improves brain GSH levels, reduces oxidative stress markers in brains of APP/PS1 transgenic mice, a mouse model...

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Detalles Bibliográficos
Autores principales: Christopher Kwon, Ye In, Xie, Wei, Zhu, Haizhou, Xie, Jiashu, Shinn, Keaton, Juckel, Nicholas, Vince, Robert, More, Swati S., Lee, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614797/
https://www.ncbi.nlm.nih.gov/pubmed/34829667
http://dx.doi.org/10.3390/antiox10111796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614797/
https://www.ncbi.nlm.nih.gov/pubmed/34829667
http://dx.doi.org/10.3390/antiox10111796

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