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Translation of Pharmacodynamic Biomarkers of Antibiotic Efficacy in Specific Populations to Optimize Doses

Antibiotic efficacy determination in clinical trials often relies on non-inferiority designs because they afford smaller study sample sizes. These efficacy studies tend to exclude patients within specific populations or include too few patients to discern potential differences in their clinical outc...

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Detalles Bibliográficos
Autores principales: Pai, Manjunath P., Crass, Ryan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614818/
https://www.ncbi.nlm.nih.gov/pubmed/34827306
http://dx.doi.org/10.3390/antibiotics10111368