Bioengineered System for High Throughput Screening of Kv1 Ion Channel Blockers

Screening drug candidates for their affinity and selectivity for a certain binding site is a crucial step in developing targeted therapy. Here, we created a screening assay for receptor binding that can be easily scaled up and automated for the high throughput screening of Kv channel blockers. It is...

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Detalles Bibliográficos
Autores principales: Sharonov, George V., Nekrasova, Oksana V., Kudryashova, Ksenia S., Kirpichnikov, Mikhail P., Feofanov, Alexey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614864/
https://www.ncbi.nlm.nih.gov/pubmed/34821753
http://dx.doi.org/10.3390/bioengineering8110187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614864/
https://www.ncbi.nlm.nih.gov/pubmed/34821753
http://dx.doi.org/10.3390/bioengineering8110187

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