S1P/S1P(2) Signaling Axis Regulates Both NLRP3 Upregulation and NLRP3 Inflammasome Activation in Macrophages Primed with Lipopolysaccharide

The activation of NLRP3 inflammasome is a key factor for various inflammatory diseases. Here, we provide experimental evidence supporting the regulatory role of sphingosine-1-phosphate (S1P) in NLRP3 inflammasome activation in mouse bone-marrow-derived macrophages (BMDMs), along with the S1P recepto...

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Detalles Bibliográficos
Autores principales: Lee, Chi-Ho, Choi, Ji Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614891/
https://www.ncbi.nlm.nih.gov/pubmed/34829577
http://dx.doi.org/10.3390/antiox10111706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614891/
https://www.ncbi.nlm.nih.gov/pubmed/34829577
http://dx.doi.org/10.3390/antiox10111706

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