Calcium Dobesilate Modulates PKCδ-NADPH Oxidase- MAPK-NF-κB Signaling Pathway to Reduce CD14, TLR4, and MMP9 Expression during Monocyte-to-Macrophage Differentiation: Potential Therapeutic Implications for Atherosclerosis

Monocyte-to-macrophage differentiation results in the secretion of various inflammatory mediators and oxidative stress molecules necessary for atherosclerosis pathogenesis. Consequently, this differentiation represents a potential clinical target in atherosclerosis. Calcium dobesilate (CaD), an esta...

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Detalles Bibliográficos
Autores principales: Njau, Florence, Haller, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615002/
https://www.ncbi.nlm.nih.gov/pubmed/34829669
http://dx.doi.org/10.3390/antiox10111798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615002/
https://www.ncbi.nlm.nih.gov/pubmed/34829669
http://dx.doi.org/10.3390/antiox10111798

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