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Amyloid-β 25-35 Induces Neurotoxicity through the Up-Regulation of Astrocytic System X(c)(−)

Amyloid-β (Aβ) deposition, a hallmark of Alzheimer’s disease, is known to induce free radical production and oxidative stress, leading to neuronal damage. During oxidative stress, several cell types (including astrocytes) can activate the nuclear factor erythroid 2-related factor 2 (Nrf2), a regulat...

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Detalles Bibliográficos
Autores principales: D’Ezio, Veronica, Colasanti, Marco, Persichini, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615014/
https://www.ncbi.nlm.nih.gov/pubmed/34829555
http://dx.doi.org/10.3390/antiox10111685