MnTnHex-2-PyP(5+), Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways

Tumor migration and invasion induced by the epithelial-to-mesenchymal transition (EMT) are prerequisites for metastasis. Here, we investigated the inhibitory effect of a mimic of superoxide dismutase (SOD), cationic Mn(III) ortho-substituted N-n-hexylpyridylporphyrin (MnTnHex-2-PyP(5+), MnHex) on th...

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Detalles Bibliográficos
Autores principales: Shin, Sung-Won, Choi, Changhoon, Kim, Hakyoung, Kim, Yeeun, Park, Sohee, Kim, Shin-Yeong, Batinic-Haberle, Ines, Park, Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615021/
https://www.ncbi.nlm.nih.gov/pubmed/34829640
http://dx.doi.org/10.3390/antiox10111769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615021/
https://www.ncbi.nlm.nih.gov/pubmed/34829640
http://dx.doi.org/10.3390/antiox10111769

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