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Dietary Iron Overload and Hfe(−/−) Related Hemochromatosis Alter Hepatic Mitochondrial Function

Iron is an essential co-factor for many cellular metabolic processes, and mitochondria are main sites of utilization. Iron accumulation promotes production of reactive oxygen species (ROS) via the catalytic activity of iron species. Herein, we investigated the consequences of dietary and genetic iro...

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Detalles Bibliográficos
Autores principales: Fischer, Christine, Volani, Chiara, Komlódi, Timea, Seifert, Markus, Demetz, Egon, Valente de Souza, Lara, Auer, Kristina, Petzer, Verena, von Raffay, Laura, Moser, Patrizia, Gnaiger, Erich, Weiss, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615072/
https://www.ncbi.nlm.nih.gov/pubmed/34829689
http://dx.doi.org/10.3390/antiox10111818