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Truncated Milk Fat Globule-EGF-like Factor 8 Ameliorates Liver Fibrosis via Inhibition of Integrin-TGFβ Receptor Interaction

Milk fat globule-EGF factor 8 (MFG-E8) protein is known as an immunomodulator in various diseases, and we previously demonstrated the anti-fibrotic role of MFG-E8 in liver disease. Here, we present a truncated form of MFG-E8 that provides an advanced therapeutic benefit in treating liver fibrosis. T...

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Detalles Bibliográficos
Autores principales: An, Geun Ho, Lee, Jaehun, Jin, Xiong, Chung, Jinwoo, Kim, Joon-Chul, Park, Jung-Hyuck, Kim, Minkyung, Han, Choongseong, Kim, Jong-Hoon, Woo, Dong-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615163/
https://www.ncbi.nlm.nih.gov/pubmed/34829758
http://dx.doi.org/10.3390/biomedicines9111529