Cargando…

Truncated Milk Fat Globule-EGF-like Factor 8 Ameliorates Liver Fibrosis via Inhibition of Integrin-TGFβ Receptor Interaction

Milk fat globule-EGF factor 8 (MFG-E8) protein is known as an immunomodulator in various diseases, and we previously demonstrated the anti-fibrotic role of MFG-E8 in liver disease. Here, we present a truncated form of MFG-E8 that provides an advanced therapeutic benefit in treating liver fibrosis. T...

Descripción completa

Detalles Bibliográficos
Autores principales:	An, Geun Ho, Lee, Jaehun, Jin, Xiong, Chung, Jinwoo, Kim, Joon-Chul, Park, Jung-Hyuck, Kim, Minkyung, Han, Choongseong, Kim, Jong-Hoon, Woo, Dong-Hun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615163/ https://www.ncbi.nlm.nih.gov/pubmed/34829758 http://dx.doi.org/10.3390/biomedicines9111529

Ejemplares similares

Milk Fat Globule-EGF Factor 8 Contributes to Progression of Hepatocellular Carcinoma
por: Ko, Duck Sung, et al.
Publicado: (2020)

Milk Fat Globule-Epidermal Growth Factor VIII Ameliorates Brain Injury in the Subacute Phase of Cerebral Ischemia in an Animal Model
por: Choi, Jong-Il, et al.
Publicado: (2020)

Serum milk fat globule-EGF factor 8 protein as a potential biomarker for metabolic syndrome
por: Lee, Han Ah, et al.
Publicado: (2021)

The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity
por: Li, Endong, et al.
Publicado: (2012)

Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis
por: Ren, Yifan, et al.
Publicado: (2021)

Reduction in milk fat globule-EGF factor 8 inhibits triple-negative breast cancer cell viability and migration
por: Yang, Yong, et al.
Publicado: (2019)

The Immunological Role of Milk Fat Globule Membrane
por: Cavaletto, Maria, et al.
Publicado: (2022)

Serum milk fat globule-EGF factor 8 (MFG-E8) as a diagnostic and prognostic biomarker in patients with hepatocellular carcinoma
por: Shimagaki, Tomonari, et al.
Publicado: (2019)

Milk Fat Globule-EGF Factor 8 Alleviates Pancreatic Fibrosis by Inhibiting ER Stress-Induced Chaperone-Mediated Autophagy in Mice
por: Ren, Yifan, et al.
Publicado: (2021)

Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury
por: Gao, Yong-Yue, et al.
Publicado: (2018)

Milk Fat Globule-EGF Factor VIII Attenuates CNS Injury by Promoting Neural Stem Cell Proliferation and Migration after Cerebral Ischemia
por: Cheyuo, Cletus, et al.
Publicado: (2015)

Milk fat globule-EGF factor 8 suppresses the aberrant immune response of systemic lupus erythematosus-derived neutrophils and associated tissue damage
por: Huang, Wei, et al.
Publicado: (2017)

The Healing Effect of Human Milk Fat Globule-EGF Factor 8 Protein (MFG-E8) in A Rat Model of Parkinson’s Disease
por: Nakashima, Yoshiki, et al.
Publicado: (2018)

Alterations in expression of endometrial milk fat globule-EGF factor 8 (MFG-E8) and leukemia inhibitory factor (LIF) in patients with infertility and endometriosis
por: Schmitz, Carla Regina, et al.
Publicado: (2017)

Cigarette smoke attenuates phagocytic ability of macrophages through down-regulating Milk fat globule-EGF factor 8 (MFG-E8) expressions
por: Wang, Yueqin, et al.
Publicado: (2017)

Recombinant human milk fat globule-EGF factor VIII (rhMFG-E8) as a therapy for sepsis after acute exposure to alcohol
por: Chaung, Wayne W., et al.
Publicado: (2019)

Roles of Milk Fat Globule Membrane on Fat Digestion and Infant Nutrition
por: Chai, Changhoon, et al.
Publicado: (2022)

Benefits of Lactoferrin, Osteopontin and Milk Fat Globule Membranes for Infants
por: Demmelmair, Hans, et al.
Publicado: (2017)

Progesterone Regulation of Milk Fat Globule Size Is VLDL Dependent
por: Argov-Argaman, Nurit, et al.
Publicado: (2020)

Shiga Toxin-Producing Escherichia coli and Milk Fat Globules
por: Bagel, Arthur, et al.
Publicado: (2022)

Whole Goat Milk as a Source of Fat and Milk Fat Globule Membrane in Infant Formula
por: Gallier, Sophie, et al.
Publicado: (2020)

Brain–immune–gut benefits with early life supplementation of milk fat globule membrane
por: Mohamed, Hamid Jan Jan, et al.
Publicado: (2022)

Is increased fat content of hindmilk due to the size or the number of milk fat globules?
por: Mizuno, Katsumi, et al.
Publicado: (2009)

Compositional Dynamics of the Milk Fat Globule and Its Role in Infant Development
por: Lee, Hanna, et al.
Publicado: (2018)

Advancement on Milk Fat Globule Membrane: Separation, Identification, and Functional Properties
por: Wang, Cong, et al.
Publicado: (2022)

Milk Fat Content and DGAT1 Genotype Determine Lipid Composition of the Milk Fat Globule Membrane
por: Argov-Argaman, Nurit, et al.
Publicado: (2013)

Milk fat globule membrane plus milk fat increase docosahexaenoic acid availability in infant formulas
por: Gázquez, Antonio, et al.
Publicado: (2022)

Quantitative Label-Free Proteomic Analysis of Milk Fat Globule Membrane in Donkey and Human Milk
por: Zhang, Xinhao, et al.
Publicado: (2021)

Evolution of milk composition, milk fat globule size, and free fatty acids during milking of dairy cows
por: Hurtaud, C., et al.
Publicado: (2020)

Enzymic characteristics of fat globule membranes from bovine colostrum and bovine milk
Publicado: (1977)

Ultrastructural and immunocytochemical evidence for the reorganisation of the milk fat globule membrane after secretion
por: Wooding, F. B. Peter, et al.
Publicado: (2016)

The endoplasmic reticulum and casein-containing vesicles contribute to milk fat globule membrane
por: Honvo-Houéto, Edith, et al.
Publicado: (2016)

Characterization of difference in structure and function of fresh and mastitic bovine milk fat globules
por: Verma, Aparna, et al.
Publicado: (2019)

Milk Fat Globule Membrane Supplementation in Children: Systematic Review with Meta-Analysis
por: Ambrożej, Dominika, et al.
Publicado: (2021)

Changes in Human Milk Fat Globule Composition Throughout Lactation: A Review
por: Thum, Caroline, et al.
Publicado: (2022)

Bioactive Functions of Lipids in the Milk Fat Globule Membrane: A Comprehensive Review
por: Pan, Junyu, et al.
Publicado: (2023)

The Effect of Milking Frequency, Breed, and Stage of Lactation on the Milk Fat Globule Size and Fatty Acid Composition in Sheep’s Milk
por: Massouras, Theofilos, et al.
Publicado: (2023)

Comparative Proteomics of Milk Fat Globule Membrane Proteins from Transgenic Cloned Cattle
por: Sui, Shunchao, et al.
Publicado: (2014)

Improving Human Health with Milk Fat Globule Membrane, Lactic Acid Bacteria, and Bifidobacteria
por: Kosmerl, Erica, et al.
Publicado: (2021)

The Impact of Milk Fat Globule Membrane with Exercise on Age-Related Degeneration of Neuromuscular Junctions
por: Sugita, Satoshi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p4itvjntqa8akadfofh2ldqsce