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Siglecs as Therapeutic Targets in Cancer

SIMPLE SUMMARY: Hyperglycosylated cancer cells are often decorated with abundant sialic acids, which are recognized by Sialic acid binding immunoglobulin type lectins (Siglecs) expressed on immune cells. As sialic acids are normally expressed on almost all cell types, Siglecs can function as recepto...

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Detalles Bibliográficos
Autores principales: Lim, Jackwee, Sari-Ak, Duygu, Bagga, Tanaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615218/
https://www.ncbi.nlm.nih.gov/pubmed/34827170
http://dx.doi.org/10.3390/biology10111178