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Orai1–STIM1 Regulates Increased Ca(2+) Mobilization, Leading to Contractile Duchenne Muscular Dystrophy Phenotypes in Patient-Derived Induced Pluripotent Stem Cells
Ca(2+) overload is one of the factors leading to Duchenne muscular dystrophy (DMD) pathogenesis. However, the molecular targets of dystrophin deficiency-dependent Ca(2+) overload and the correlation between Ca(2+) overload and contractile DMD phenotypes in in vitro human models remain largely elusiv...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615222/ https://www.ncbi.nlm.nih.gov/pubmed/34829817 http://dx.doi.org/10.3390/biomedicines9111589 |