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The Neuro-Protective Effects of the TSPO Ligands CB86 and CB204 on 6-OHDA-Induced PC12 Cell Death as an In Vitro Model for Parkinson’s Disease

SIMPLE SUMMARY: Aims and objectives: For this study, we hypothesized that the two TSPO ligands CB86 and CB204 can inhibit cellular apoptosis and necrosis by in in vitro cellular PD model of undifferentiated PC12 cells exposed to 6-hydroxydopamine (6-OHDA, 80 µM). The two TSPO ligands CB86 and CB204...

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Detalles Bibliográficos
Autores principales: Monga, Sheelu, Denora, Nunzio, Laquintana, Valentino, Yashaev, Rami, Weizman, Abraham, Gavish, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615274/
https://www.ncbi.nlm.nih.gov/pubmed/34827176
http://dx.doi.org/10.3390/biology10111183