Synthetic Tryptanthrin Derivatives Induce Cell Cycle Arrest and Apoptosis via Akt and MAPKs in Human Hepatocellular Carcinoma Cells

Trytanthrin, found in Ban-Lan-Gen, is a natural product containing an indoloquinazoline moiety and has been shown to possess anti-inflammatory and anti-viral activities. Chronic inflammation and hepatitis B are known to be associated with the progression of hepatocellular carcinoma (HCC). In this st...

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Detalles Bibliográficos
Autores principales: Gao, Jing-Yan, Chang, Chih-Shiang, Lien, Jin-Cherng, Chen, Ting-Wei, Hu, Jing-Lan, Weng, Jing-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615277/
https://www.ncbi.nlm.nih.gov/pubmed/34829756
http://dx.doi.org/10.3390/biomedicines9111527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615277/
https://www.ncbi.nlm.nih.gov/pubmed/34829756
http://dx.doi.org/10.3390/biomedicines9111527

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