Long-Term PDE-5A Inhibition Improves Myofilament Function in Left and Right Ventricular Cardiomyocytes through Partially Different Mechanisms in Diabetic Rat Hearts

Heart failure with preserved ejection fraction (HFpEF) and right ventricular (RV) dysfunction are frequent complications of diabetic cardiomyopathy. Here we aimed to characterize RV and left ventricular (LV) remodeling and its prevention by vardenafil (a long-acting phosphodiesterase-5A (PDE-5A) inh...

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Detalles Bibliográficos
Autores principales: Bódi, Beáta, Kovács, Árpád, Gulyás, Hajnalka, Mártha, Lilla, Tóth, Attila, Mátyás, Csaba, Barta, Bálint András, Oláh, Attila, Merkely, Béla, Radovits, Tamás, Papp, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615283/
https://www.ncbi.nlm.nih.gov/pubmed/34829647
http://dx.doi.org/10.3390/antiox10111776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615283/
https://www.ncbi.nlm.nih.gov/pubmed/34829647
http://dx.doi.org/10.3390/antiox10111776

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