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Ca(2+)/Sr(2+) Selectivity in Calcium-Sensing Receptor (CaSR): Implications for Strontium’s Anti-Osteoporosis Effect

The extracellular calcium-sensing receptor (CaSR) controls vital bone cell functions such as cell growth, differentiation and apoptosis. The binding of the native agonist (Ca(2+)) to CaSR activates the receptor, which undergoes structural changes that trigger a cascade of events along the cellular s...

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Detalles Bibliográficos
Autores principales: Cheshmedzhieva, Diana, Ilieva, Sonia, Permyakov, Eugene A., Permyakov, Sergei E., Dudev, Todor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615369/
https://www.ncbi.nlm.nih.gov/pubmed/34827574
http://dx.doi.org/10.3390/biom11111576