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Posttranslational Modifications in PD-L1 Turnover and Function: From Cradle to Grave

Programmed death-ligand 1 (PD-L1) is one of the most classic immune checkpoint molecules. Cancer cells express PD-L1 to inhibit the activity of effector T cells’ cytotoxicity through programmed death 1 (PD-1) engagement in exposure to inflammatory cytokines. PD-L1 expression levels on cancer cells m...

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Detalles Bibliográficos
Autores principales: Yu, Xinfang, Li, Wei, Young, Ken H., Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615371/
https://www.ncbi.nlm.nih.gov/pubmed/34829931
http://dx.doi.org/10.3390/biomedicines9111702