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Dose-Dependent Effects of a Novel Selective EP(4) Prostaglandin Receptor Agonist on Treatment of Critical Size Femoral Bone Defects in a Rat Model

Difficulties in treating pseudarthrosis and critical bone defects are still evident in physicians’ clinical routines. Bone morphogenetic protein 2 (BMP-2) has shown promising osteoinductive results but also considerable side effects, not unexpected given that it is a morphogen. Thus, the bone regene...

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Detalles Bibliográficos
Autores principales: Vater, Corina, Mehnert, Elisabeth, Bretschneider, Henriette, Bolte, Julia, Findeisen, Lisa, Matuszewski, Lucas-Maximilian, Zwingenberger, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615441/
https://www.ncbi.nlm.nih.gov/pubmed/34829941
http://dx.doi.org/10.3390/biomedicines9111712