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Role of Inflammation and Redox Status on Doxorubicin-Induced Cardiotoxicity in Infant and Adult CD-1 Male Mice

Doxorubicin (DOX) is a topoisomerase II inhibitor commonly used in the treatment of several types of cancer. Despite its efficacy, DOX can potentially cause fatal adverse effects, like cardiotoxicity. This work aimed to assess the role of inflammation in DOX-treated infant and adult mice and its pos...

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Detalles Bibliográficos
Autores principales: Reis-Mendes, Ana, Padrão, Ana Isabel, Duarte, José Alberto, Gonçalves-Monteiro, Salomé, Duarte-Araújo, Margarida, Remião, Fernando, Carvalho, Félix, Sousa, Emília, Bastos, Maria Lourdes, Costa, Vera Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615472/
https://www.ncbi.nlm.nih.gov/pubmed/34827723
http://dx.doi.org/10.3390/biom11111725