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Mechanical Stretching-Induced Traumatic Brain Injury Is Mediated by the Formation of GSK-3β-Tau Complex to Impair Insulin Signaling Transduction

Traumatic brain injury confers a significant and growing public health burden. It is a major environmental risk factor for dementia. Nonetheless, the mechanism by which primary mechanical injury leads to neurodegeneration and an increased risk of dementia-related diseases is unclear. Thus, we aimed...

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Detalles Bibliográficos
Autores principales: Cheng, Pei-Wen, Wu, Yi-Chung, Wong, Tzyy-Yue, Sun, Gwo-Ching, Tseng, Ching-Jiunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615493/
https://www.ncbi.nlm.nih.gov/pubmed/34829879
http://dx.doi.org/10.3390/biomedicines9111650