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p53-Mediated Radiosensitization of (177)Lu-DOTATATE in Neuroblastoma Tumor Spheroids

p53 is involved in DNA damage response and is an exciting target for radiosensitization in cancer. Targeted radionuclide therapy against somatostatin receptors with (177)Lu-DOTATATE is currently being explored as a treatment for neuroblastoma. The aim of this study was to investigate the novel p53-s...

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Detalles Bibliográficos
Autores principales: Lundsten, Sara, Berglund, Hanna, Jha, Preeti, Krona, Cecilia, Hariri, Mehran, Nelander, Sven, Lane, David P., Nestor, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615514/
https://www.ncbi.nlm.nih.gov/pubmed/34827693
http://dx.doi.org/10.3390/biom11111695