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Mitochondria-Mediated Apoptosis of HCC Cells Triggered by Knockdown of Glutamate Dehydrogenase 1: Perspective for Its Inhibition through Quercetin and Permethylated Anigopreissin A

Metabolic reprogramming is a hallmark of cancer cells required to ensure high energy needs and the maintenance of redox balance. A relevant metabolic change of cancer cell bioenergetics is the increase in glutamine metabolism. Hepatocellular carcinoma (HCC), one of the most lethal cancer and which r...

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Detalles Bibliográficos
Autores principales: Marsico, Michela, Santarsiero, Anna, Pappalardo, Ilaria, Convertini, Paolo, Chiummiento, Lucia, Sardone, Alessandra, Di Noia, Maria Antonietta, Infantino, Vittoria, Todisco, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615521/
https://www.ncbi.nlm.nih.gov/pubmed/34829892
http://dx.doi.org/10.3390/biomedicines9111664