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Emergence and Enhancement of Ultrasensitivity through Posttranslational Modulation of Protein Stability
Signal amplification in biomolecular networks converts a linear input to a steeply sigmoid output and is central to a number of cellular functions including proliferation, differentiation, homeostasis, adaptation, and biological rhythms. One canonical signal amplifying motif is zero-order ultrasensi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615576/ https://www.ncbi.nlm.nih.gov/pubmed/34827739 http://dx.doi.org/10.3390/biom11111741 |