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Emergence and Enhancement of Ultrasensitivity through Posttranslational Modulation of Protein Stability

Signal amplification in biomolecular networks converts a linear input to a steeply sigmoid output and is central to a number of cellular functions including proliferation, differentiation, homeostasis, adaptation, and biological rhythms. One canonical signal amplifying motif is zero-order ultrasensi...

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Detalles Bibliográficos
Autores principales: Kumbale, Carla M., Voit, Eberhard O., Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615576/
https://www.ncbi.nlm.nih.gov/pubmed/34827739
http://dx.doi.org/10.3390/biom11111741