Epigenetic Therapy Augments Classic Chemotherapy in Suppressing the Growth of 3D High-Grade Serous Ovarian Cancer Spheroids over an Extended Period of Time

Recurrent high-grade serous ovarian cancer (HGSC) is clinically very challenging and prematurely shortens patients’ lives. Recurrent ovarian cancer is characterized by high tumor heterogeneity; therefore, it is susceptible to epigenetic therapy in classic 2D tissue culture and rodent models. Unfortu...

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Detalles Bibliográficos
Autores principales: Bilbao, Michelle, Katz, Chelsea, Kass, Stephanie L., Smith, Devon, Hunter, Krystal, Warshal, David, Aikins, James K., Ostrovsky, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615646/
https://www.ncbi.nlm.nih.gov/pubmed/34827710
http://dx.doi.org/10.3390/biom11111711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615646/
https://www.ncbi.nlm.nih.gov/pubmed/34827710
http://dx.doi.org/10.3390/biom11111711

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