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CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement

Objective: To assess whether phosphorylated neurofilament heavy chain (pNfH) can discriminate different upper motor neuron (UMN) syndromes, namely, ALS, UMN-predominant ALS, primary lateral sclerosis (PLS) and hereditary spastic paraparesis (hSP) and to test the prognostic value of pNfH in UMN disea...

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Detalles Bibliográficos
Autores principales: Simonini, Cecilia, Zucchi, Elisabetta, Bedin, Roberta, Martinelli, Ilaria, Gianferrari, Giulia, Fini, Nicola, Sorarù, Gianni, Liguori, Rocco, Vacchiano, Veria, Mandrioli, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615649/
https://www.ncbi.nlm.nih.gov/pubmed/34829852
http://dx.doi.org/10.3390/biomedicines9111623