Genetic Determinants of Plasma Low-Density Lipoprotein Cholesterol Levels: Monogenicity, Polygenicity, and “Missing” Heritability

Changes in plasma low-density lipoprotein cholesterol (LDL-c) levels relate to a high risk of developing some common and complex diseases. LDL-c, as a quantitative trait, is multifactorial and depends on both genetic and environmental factors. In the pregenomic age, targeted genes were used to detec...

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Detalles Bibliográficos
Autor principal: Martín-Campos, Jesús Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615680/
https://www.ncbi.nlm.nih.gov/pubmed/34829957
http://dx.doi.org/10.3390/biomedicines9111728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615680/
https://www.ncbi.nlm.nih.gov/pubmed/34829957
http://dx.doi.org/10.3390/biomedicines9111728

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