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The Membrane-Bound Notch Regulator Mnr Supports Notch Cleavage and Signaling Activity in Drosophila melanogaster

The Notch signaling pathway is pivotal to cellular differentiation. Activation of this pathway involves proteolysis of the Notch receptor and the release of the biologically active Notch intracellular domain, acting as a transcriptional co-activator of Notch target genes. While the regulation of Not...

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Detalles Bibliográficos
Autores principales: Nagel, Anja C., Müller, Dominik, Zimmermann, Mirjam, Preiss, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615698/
https://www.ncbi.nlm.nih.gov/pubmed/34827670
http://dx.doi.org/10.3390/biom11111672