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The Membrane-Bound Notch Regulator Mnr Supports Notch Cleavage and Signaling Activity in Drosophila melanogaster
The Notch signaling pathway is pivotal to cellular differentiation. Activation of this pathway involves proteolysis of the Notch receptor and the release of the biologically active Notch intracellular domain, acting as a transcriptional co-activator of Notch target genes. While the regulation of Not...
Autores principales: | Nagel, Anja C., Müller, Dominik, Zimmermann, Mirjam, Preiss, Anette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615698/ https://www.ncbi.nlm.nih.gov/pubmed/34827670 http://dx.doi.org/10.3390/biom11111672 |
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