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Modeling Prostate Cancer Treatment Responses in the Organoid Era: 3D Environment Impacts Drug Testing

Organoid-based studies have revolutionized in vitro preclinical research and hold great promise for the cancer research field, including prostate cancer (PCa). However, experimental variability in organoid drug testing complicates reproducibility. For example, we observed PCa organoids to be less af...

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Detalles Bibliográficos
Autores principales: Van Hemelryk, Annelies, Mout, Lisanne, Erkens-Schulze, Sigrun, French, Pim J., van Weerden, Wytske M., van Royen, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615701/
https://www.ncbi.nlm.nih.gov/pubmed/34827570
http://dx.doi.org/10.3390/biom11111572