Agent Clustering Strategy Based on Metabolic Flux Distribution and Transcriptome Expression for Novel Drug Development

The network module-based method has been used for drug repositioning. The traditional drug repositioning method only uses the gene characteristics of the drug but ignores the drug-triggered metabolic changes. The metabolic network systematically characterizes the connection between genes, proteins,...

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Detalles Bibliográficos
Autores principales: Ruan, Yao, Chen, Xiao-Hui, Jiang, Feng, Liu, Yan-Guang, Liang, Xiao-Long, Lv, Bo-Min, Zhang, Hong-Yu, Zhang, Qing-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615746/
https://www.ncbi.nlm.nih.gov/pubmed/34829869
http://dx.doi.org/10.3390/biomedicines9111640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615746/
https://www.ncbi.nlm.nih.gov/pubmed/34829869
http://dx.doi.org/10.3390/biomedicines9111640

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